UNDERGRADUATE 

Monash University - 1965-1969

Preclinical 1965-1967
B Med Sci 1968
Supervisors - GC Smith and G Fink
Thesis - "The role of catecholamines in the hypothalamic control of the pituitary-adrenal axis".
 
Clinical 1969
Six months of fourth year medicine - Alfred, Queen Victoria and Prince Henry's Hospitals
 

Oxford University - 1969-1974

Balliol College
First BM - exemption
BA Physiology, Honours Schools 1971
 
Clinical
Radcliffe Infirmary Oxford
Second BM, B Ch 1974
MA 1979
Doctorate of Medicine 1986 (accepted for supplication)
Thesis - "Dietary carbohydrate and blood glucose control in Diabetes Mellitus"

POST GRADUATION

Provisional Registration (UK) July 1974
Registration (UK) July 1975
MRCP (UK) February 1977
Registration (Victoria) February 1979
FRACP (Endocrinology) February 1981
FRCP (UK) 1996

HONOURS, PRIZES AND SCHOLARSHIPS

Monash University

High distinction  - Physics and chemistry 1965
Distinction - Mathematical methods and biology 1965
University Prize - Physics 1965
Credit - Anatomy 1966
Distinction - Biochemistry 1967
Distinction - Physiology 1967
Credit - Functional Histology
Credit - Neurology
National Health & Medical Research Council Scholarships 1968
1st Class Honour - B Med Sci 1969
                                                                                                                       

Oxford University

Oxford University Commonwealth Medical Scholarship 1969-1974
1st Class Honour - BA 1971
Lepra Essay Prize 1972 (essay competition in Oxbridge and London Universities                                             
sponsored by Lepra - a charitable organisation supporting research into leprosy)
Second BM - only awarded as a pass degree in Oxford
 

Medical Research Centre, Prince Henry's Hospital, Melbourne

National Health & Medical Research Council Postgraduate Scholarship 1981
  

PAST OFFICES

ENGLAND

Pre-Registration - 12 month rotation

      House Surgeon - General Surgery/Urology
      Northampton General Hospital, Northampton.
      Mr. J. Fergus August 1974-January 1975
 
      House Physician - General Medicine, Diabetes, Endocrinology, Cardiology
      Radcliffe Infirmary, Oxford.  Drs J Badenoch, TDR Hockaday and
      B Gribbin.  February 1975-July 1975

Post Registration

      Senior House Officer
      United Oxford Hospitals and University Department of neurology, Churchill Hospital, Oxford
      Professor B Matthews, Drs. D W Whitty and J Spalding.  August 1975-July 1976
      Regional neurology service for acute and chronic neurological disorders
 
      Senior House Officer
      Department of Nephrology, Churchill Hospital, Oxford
      Drs D Oliver and JGG Ledingham.  August 1976-February 1977
      Regional nephrology service for acute and chronic renal
      failure, renal dialysis and transplant service
 
      Senior House Officer
      Nuffield Department of Medicine, University of Oxford,
      Radcliffe Infirmary, Oxford
      General medicine, clinical haematology and diabetes
      Professor D Weatherall, Drs JGG Ledingham, S Callender and RC Turner.                              
      February 1977-July 1977
      Acute medical service receiving for the Oxfordshire region
 
      Research Registrar and Registrar to Diabetic Clinic                                                    
      Department of the Regius Professor of Medicine
      Radcliffe Infirmary and University of Oxford    
      August 1977-January 1979
      Supervisors:DrS R C Turner and JI Mann                                                             
                                                                                   

AUSTRALIA

Endocrine Registrar
Department of Endocrinology and Diabetes, Prince Henry's Hospital, Melbourne
Professor HG Burger, Drs G Ennis and DW Lording.  February 1979-January 1981
 
Lipid Clinic, Prince Henry's Hospital, Melbourne
Professor ML Wahlqvist.  February 1979-January 1981
 
Visiting Clinical Assistant Diabetes Clinic
St Vincent's Hospital, Melbourne
Dr F Alford.  February 1981-December 1981
 
Junior Specialist Fellow in Endocrinology
Prince Henry's Hospital, Melbourne
February 1981-December 1981
 
Assistant Physician
Department of Endocrinology and Diabetes, Prince Henry's Hospital, Melbourne
January 1982-December 1982
 
NH & MRC Postgraduate Medical Research Scholar
Medical Research Centre, Prince Henry's Hospital, Melbourne
February 1981-August 1983
 
Visiting Clinical Assistant
Ewen Downie Metabolic Unit, Alfred Hospital, Melbourne
January 1982-June 1984
 
Endocrinologist
Reproductive Medical Clinic, Prince Henry's Hospital/now Monash Medical Centre, Clayton
August 1980-December 1990
 
Consultant Endocrinologist
Department of Endocrinology and Diabetes, Prince Henry's Hospital, Melbourne
January 1982- September 1991
 
Consultant Endocrinologist
Monash Medical Centre, Clayton and Moorabbin Campuses
1983-September 1997
 
Consulting Endocrinologist
Box Hill Hospital
September 1984- continuing
 
General Physician
Box Hill Hospital                                                                                                           
Appointed 1991- continuing
 
Director of Diabetes and Endocrinology Unit
Box Hill Hospital
December 1992-2007 (retired)         
 
Principal Investigator Diabetes Trials
Eastern Clinical Reseach Unit, Monash University and Box Hill Hospital                                    
Principal investigator for range of clinical trials involving 

• Insulin analogues
• GLP-1 analogues
• DPP-4 inhibitors
• CVD reduction in Diabetes (type 2)
• Sleep Apnoea in Diabetes (type 2)
• Alpha Glucokinase Activators
  
• Diabetes Prevention (type 2)

PRIVATE PRACTICE  

Suite 33, 50 Nelson Road,
Box Hill, Vic., 3128 

SOCIETY MEMBERSHIPS 

1977                 British Diabetes Association
1978                 European Association for the Study of Diabetes
1979                 Australian Diabetes Society
1982                 Endocrine Society of Australia
1984                 Convenor of Local Organising Committee for Annual Meeting of ADS (Melbourne)
1995                 American Diabetes Association
  

PUBLICATIONS

1970

1          G C Smith and R W Simpson
            Monoamine fluorescence in median eminence of foetal,neonatal and adult rats
            Z Zelforsch, 104: 541
 
1977
 
2          R W Simpson, T D R Hockaday and K G M M Alberti
            Metabolic and hormonal responses to glucagon in diabetes mellitus
            Clinical Endocrinology, 7: 203
 
1978
 
3          R W Simpson, C Huang and D Graeme-Smith
            Psitticosis masquerading as rheumatic fever British Medical Journal, 1: 694
 

4          R W Simpson, J I Mann, T D R Hockaday, J M Hockaday,                                        
            R C Turner and R Jelfs
            Lipid abnormalities in untreated maturity onset diabetes and the effect of treatment
            Diabetologia, 16: 101                                                                                         
 
1979
 
5          R A Moore, R W Simpson and J Mann
            HDL cholesterol and coronary risk factors
            Lancet, 1: 409
 
6          R W Simpson and A Lang
            Etiology and treatment of diabetes mellitus (short review)
            Druggist and Chemist, May                                                                                
 
7          R A Moore, W A F Penfold, R W Simpson, R D Simpson,
            J I Mann and R C Turner
            High density lipoprotein, lipid and carbohydrate metabolism during increasing fitness
            Annals of Clinical Biochemistry, 16: 76.
                                               
8          R W Simpson, J I Mann, J Eaton R A Moore, R D Carter
            and T D R Hockaday
            Improved glucose control in maturity onset diabetes treated with high carbohydrate modified fat diets
            British Medical Journal, 1: 1753
                                                                                                                       
9          R W Simpson, J I Mann, J Eaton, R D Carter and
            T D R Hockaday
            High carbohydrate diets and insulin dependent diabetes
            British Medical Journal, 2: 523
 
10         M Phillips, R W Simpson, R R Holman and R C Turner
            A simple and rational twice daily insulin regime
            Quarterly Journal of Medicine, 1979, 48: 493
                                                                                                                                                                                               
11         R W Simpson
            Diabetes mellitus and dietary therapy in 1979
            International Medicine 1: 26
 
1980
 
12         R W Simpson, R A Moore, W A F Penfold and R D Carter
            Diurnal changes in blood lipoproteins in normal and diabetic subjects
            Diabetologia, 18: 35
 
13         E A Ward, M A Phillips, G M Ward, R W Simpson, R Mullins
            and R C Turner
            Clinic rather than self-monitoring of home blood samples:
            relevance of day to day variability to decision making
            Diabetes Care, 3: 171-174
 
14         S Howe-Davis, R W Simpson and R C Turner
            The fasting plasma glucose, a simple and precise index of control in maturity onset diabetes
            Diabetes Care, 3: 607-610                                                         
 

1981                                                                                                                               
 
15         H C R Simpson, R W Simpson, S Lousley, R D Carter,
            M Geekie, T D R Hockaday and J I Mann
            A high carbohydrate leguminous fibre diet improves all aspects of diabetic control
            Lancet, 1: 1
 
16         N M Thomson, R W Simpson, D Hooke and R C Atkins
            Peritoneal dialysis in the treatment of diabetic endstage renal failure In "Peritoneal Dialysis",
            ed R C Atkins, N M Thomson and P Farrell, p 345
 
17         M L Wahlqvist and R W Simpson
            The diet in diabetes
            Patient Management, August, 53-59
                                                                                                                      
18         R W Simpson, J McDonald, M L Wahlqvist, N Balazs and M Dunlop
            Effect of naturally occurring dietary fibre in Western foods on blood glucose
            Australian and New Zealand Journal of Medicine, 1981, 11: 484    
                       
19         G M Ward, R W Simpson, E A Ward and R C Turner
            Comparison of two twice daily insulin regimens:ultralente/soluble and soluble/isophane
            Diabetologia, 21: 383-386
 
1982
 
20         J D Wilson, R W Simpson, M L Wahlqvist, I Favilla and B D Tait
            Familial optic atrophy with diabetes mellitus
            Australian and New Zealand Journal of Medicine, 1982, 12: 48      
                                                                                   
21         G M Ward, R W Simpson, H C R Simpson, B A Naylor, J I Mann and R C Turner
            Insulin receptor binding increased by high carbohydrate low fat diet in non-insulin dependent diabetics
            European Journal of Clinical Investigation, 12: 93
 
22         R W Simpson
            Dietary fibre - myths and facts
            Diabetes Conquest, July, 9
 
23         R W Simpson
            Dietary carbohydrate in the treatment of diabetes
            Symposium Proc Nutr Soc Aust 7, 63-68
           
1983
 
24         P L Prince, J A Eisman and R W Simpson
            Hypercalcaemia in association with renal failure.
            The role of immobilization
            Aust N Z J Med 13, 8-10
 
25         D M de Kretser, R W Simpson, J D Wilson, G C Rennie,
            B Hudson and H G Burger
            Androgens and sexual behaviour
            Proceedings of the 10th Annual Congres of Australian
            Society for Psychosomatic Obstetrics and Gynaecology,
            49-53
 
1985
 
26         R W Simpson, J McDonald, M L Wahlqvist, L Atley and K Outch
            Physical factors have different metabolic effects in non-diabetics and diabetics
            Am J Clin Nutr 42, 462-469                                            
 

27         R W Simpson, J McDonald, M L Wahlqvist, L Atley and K Outch                               
            Macronutrients have different metabolic effects in non-diabetics and diabetics
            Am J Clin Nutr 42, 449-453
 
28         G Ennis & R W Simpson
            Management of Type 1 Diabetes.
            In Diabetes Mellitis - A Guide to Treatment.  Ed P Taft. 
            Adis Press.
 
1986
 
29         P L Cooper, M L Wahlqvist and R W Simpson
            The value of the glycaemic index in diabetes
            Patient Management, June, 119-123
 
30         P L Cooper, M L Wahlqvist and R W Simpson
            Sucrose in the diabetic diet
            In "Recent Advances in Clinical Nutrition" 2,
            ed M L Wahlqvist and A S Truswell, pp 271-283                                                   

1988
 
31         P L Cooper, M L Wahlqvist and R W Simpson
            Sucrose versus saccharin as an added sweetener in non-insulin-dependent diabetes:        
            Short and medium term metabolic effects
            Diab Med 5, 676-680
 
32         M L Wahlqvist, C S Lo, K A Myers, R W Simpson and
            J M Simpson
            Putative determinants of arterial wall compliance in NIDDM
            Diabetes Care 11, 787-790                                                         
 
33         R W Simpson, J McDonald, M L Wahlqvist, N Balasz,
            M Sissons and L Atley
            Temporal study of metabolic change when poorly controlled non-insulin-dependent
            diabetics change from low to high carbohydrate and fibre diet
            Am J Clin Nutr 48, 104-109
 
2000
 
34        R W Simpson, S Kast
            Management of Gestational Diabetes with a conservative insulin protocol
            Med J Aust 172, 11, 537-40
 
2002
 
35         S.Kast, RW Simpson
            Real-Life perfomance of Optium (Medisense) Dual –Fill test strips.
            ADEA Magazine 5,35-36

2003
 
36         R.W.Simpson, J E Shaw and  P Z Zimmet
             The prevention of type 2 diabetes-lifestyle changes or pharmacotherapy ?
             A challenge for thr 21st century.
             Diabetes Research and Clinical Practice 59, 165-180
 
37        Richard W.Simpson, Jaakko Tuomilehto, Jaana Lindstrom, Jonathan E Shaw and  Paul  Z Zimmet. 
            Prevention of Type 2 Diabetes Mellitus. In International Textbook of Diabetes.
            Ed R.A.DeFronzo, E. Ferannini, H. Keen and  PZ Zimmet. 3rd edition, 2004 John Wiley & Sons Ltd (in press)
 
 
38        Russell-Jones, J Bolinder, R Simpson, B Hylleberg and E Draeger
            Once daily basal insulin regimen with insulin detemir allows lower and more predictable fasting
            plasma glucose, combined with a lower risk of nocturnal hypoglycemia compared with
            NPH in type 1 diabetes
            (submitted for publication)
  

ABSTRACTS

1969
 
1          R W Simpson and G C Smith
            Monoamine fluorescence in median eminence of foetal and neonatal rats
            Proceedings of the Annual Meeting Australian Anatomical Society
 
2          G Fink, R W Simpson and V Lee
            Dopamine and the secretion of ACTH
            Proceedings of Annual Meeting Australian Physiology Society
            Australian Journal of Experimental Biology and Medical Science, 47: 9                  
 
3          G C Smith, L Osborne and R W Simpson
            Comparative study of the distribution of monoamines in the peri-vascular zone of the          
            median eminence of the echidna, rabbit and rat
            Proceedings of the Annual Meeting Australian Anatomical Society
            Journal of Anatomy, 106:  207 (1970)
 
1973
 
4          R W Simpson, K G M M Alberti and T D R Hockaday
            Capillary fragility and growth hormone in diabetes mellitus
            Proceedings of the Meeting of the Scientific Section of the British Diabetes Association
 
1978
 
5          R W Simpson, J Mann, J Eaton and T D R Hockaday
            Comparison in diabetes of the standard low carbohydrate diet with a modified fat-high fibre  diet
            Proceedings of Spring Meeting of the Scientific Section of the British Diabetes Association
            Proceedings of the 14th Annual Meeting of EASD (Zagrab),
            Diabetologia, 15: 270
 
1979
 
6          R W Simpson
            Improved glucose control in maturity onset diabetes treated with high-carbohydrate-           
            modified fat diet
            Medilex Digest Internal Medicine, April, 44
                                                                                   
1980
 
7          R W Simpson, J McDonald, M Dunlop, B Strauss and M Wahlqvist
            Effect of naturally occurring dietary fibre in Western foods on blood glucose levels
            Proceedings of the Annual Meeting of the Australian Diabetes Society
 
8          G M Ward, R W Simpson, E A Ward and R C Turner
            Comparison of two bd insulin regimens:  soluble/isophane and ultralente/solute
            Proceedings of the Autumn Meeting of the Scientific section of the British Diabetes Association
 

1981                                                                                                                             
 
9          R W Simpson, J McDonald, M Wahlqvist and K Outch
            Acute effects of naturally occurring leguminous fibre on carbohydrate absorption
            Proceedings of the Annual Meeting of the Australian Diabetes Society
 
1982
 
10         N M Thomson, R W Simpson and R C Atkins
            Continuous ambulatory peritoneal dialysis (CAPD) in the treatment of diabetic endstage
            renal failure (ESRF)
            Annual Meeting of the Australasian Society of Nephrology
            Aust N Z J Med 12, 329
 
11         R W Simpson, J McDonald, M L Wahlqvist and L Atley
            Chronic metabolic effect of high carbohydrate, high fibre diet in type 2 diabetics
            Proceedings of Annual Meeting of the Australian Diabetes
            Proceedings of 11th Congress of the International Diabetes Federation (Nairobi)
 
12         R W Simpson, B A K Khalid, N Kraft, L Atley and J W Funder
            Insulin binding and effector studies in human cell lines
            Proceedings of the Annual Meeting of the Endocrine Society of Australia
 
13         M Biddle, J McDonald, R W Simpson and M L Wahlqvist                                     
            Nutritional adequacy of diabetic diets in the low carbohydrate era
            Proceedings of Annual Meeting of the Australian Nutrition Society
                                   
1984
 
14         N M Thomson, R W Simpson and R C Atkins
            CAPD in the diabetic comparison with the non-diabetic on CAPD
            III International Symposium on Peritoneal Dialysis
            Washington DC                                    
 
15         P L Cooper, M L Wahlqvist and R W Simpson
            Sucrose versus saccharine as an additive sweetener,
            Metabolic study in NIDDM
            Proceedings of the Annual Meeting of the Australian Diabetes Society
 
1992
 
16         S Kast, R W Simpson and J Szymanski
            Near enough is just not good enough - QA in ward blood glucose monitoring
            Proceedings of the Annual Meeting of the Australian Diabetes Educators Association, Adelaide
 
1995
 
17         S Kast, R W Simpson, E Kenyon, A Reid and D Greig
            Developing Australian National Standards for ward BGM
            Proceedings of the Annual Meeting of the Australian Diabetes Educators Association,
            Melbourne
 
18        S Kast, R W Simpson, E Kenyon and D Greig
            Bedside blood glucose accuracy
            Proceedings of the Annual Meeting of the Australian Diabetes Educators Association,
            Melbourne
 
1996
 
19         D Winters, S Kast, R Simpson, H Newnham
            Lignocaine therapy for painful diabetic neuropathy
            Proceedings of the Annual Meeting of the Australian Diabetes Educators Association,
            Sydney
 
1997                                                                                                                
 
20         R Simpson, S Kast
            Conservative insulin management of gestational diabetes.
            Proceedings of the Australian Diabetes Society,
            Canberra
 
2000
 
21         V Viola, R Simpson, G Murphy, K Harvey
             Evaluation of the efficacy of intravenous lignocaine in the treatment of pain associated            
            with diabetic neuropathy.
            Proceedings of Australian Diabetes Society and Australian Diabetes Educators Association,
            Queensland
 
2002
 
22         Russell-Jones D, J Bolinder and R W Simpson
             Lower and more  predictable fasting blood glucose and reduced risk of nocturnal hypoglycaemia
             with once daily insulin detemir versus NPH in subjects with tyoe 1 diabetes.
             Proceedings 38th annual meeting EASD,  Budapes.t 2002
 
2003                                                                                                                           
 
23         Russell-Jones D, Bolinder J, Simpson RW, Stades A, Stender A, Hylleberg B and Draewger E 
             Once daily dosing with insulin determir offers advantages compared to NPH insulin in subjects
             with type 1 diabetes.
             Proceedings 63rd annual meeting ADA New Orleans 2003
 
 
24        Lui H, Dear A, Medcalf RL and Simpson RW
            Thiazolidinedione-mediated inhibition of PAI-1 expression in C11-STH human vascular endothelial cells:
            a possible mechanism for rosiglitazone and pioglitazone-mediated attenuation of atherosclerosis
            In the metabolic syndrome.
            Proceedings 18th congress IDF, Paris, 2003
 
25         Rando L, Newnham H and Simpson RW
             Diabetes screening amongst inpatients with cellulitis and osteomyelitis.
             Proceedings of ADS, Melbourne,2003
 
26         Kast S and Simpson RW
             Diabetes educators and clinical reseach trials
             Proceedings of ADS, Melbourne,2003